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Fei philips CM120 transmission electron microscope


Transmission Electron Microscope
with Edax Detecting Unit & Edax DX-4 Analyzer
The Philips CM120 cryo-electron microscope is a computer-controlled transmission instrument dedicated to low dose and cryo-electron microscopic observations. Low electron dose images minimize specimen damage due to electron irradiation, thus enhancing molecular level detail in negative stain and cryo images. Cryo-electron microscopy is a powerful technique applicable to subcellular particles (filaments, viruses, small organelles etc). By avoiding conventional preparative steps (fixation, dehydration, staining), it provides images that are essentially artifact-free, and in some instances with near-atomic level structural detail. The facility possesses plunge-freezing equipment for specimen preparation and a Gatan cryo-holder for specimen observations at temperatures of ~ -185o C. An integral part of the microscope is the computer-controlled goniometer CompuStage , allowing storage and recall of multiple specimen positions, greatly aiding in cryo-observation. The CM120 is equipped with a TVIPS 2Kx2K CCD camera (F224HD) for direct digital acquisition of images. The TVIPS software allows automated collection of multiple tilt images for electron tomography. A Fischione Advanced Tomography holder allows tilts up to 80o.



Fei philips CM120 transmission electron microscope Fei philips CM120 transmission electron microscope Fei philips CM120 transmission electron microscope Fei philips CM120 transmission electron microscope